Improving Stroke Outcomes: Attenuating Progression and Recurrence

Grant number: 1013612 | Funding period: 2012 - 2016

Completed

Abstract

Stroke is the second most common cause of death and major cause disability. There are few proven interventions, so we need to introduce new ones. We developed a bench to bedside program to introduce new stroke therapies and its early secondary prevention. Our general goal is to provide evidence for their effectiveness and safety. We will use animal stroke models, markers in the blood to help diagnose and predict stroke outcome and imaging to help select patients for several clinical trials.

Related publications (3)

Depression Outcomes among Patients Treated with Fluoxetine for Stroke Recovery: The AFFINITY Randomized Clinical Trial

OP Almeida, GJ Hankey, A Ford, C Etherton-Beer, L Flicker, M Hackett

2021-09-01

Importance: One in 3 adults experiences clinically significant symptoms of depression during the first year after a stroke, but ev..

Evolution of ischemic damage and behavioural deficit over 6 months after MCAo in the rat: Selecting the optimal outcomes and statistical power for multi-centre preclinical trials

SSJ Rewell, L Churilov, TK Sidon, E Aleksoska, SF Cox, MR Macleod, DW Howells

2017-02-01

Key disparities between the timing and methods of assessment in animal stroke studies and clinical trial may be part of the reason..

MR RESCUE: Is the glass half-full or half-empty?

MW Parsons, GW Albers

2013-07-01

University of Melbourne Researchers

Stephen Davis